En un trabajo italiano se describe un nuevo cannabinoide, el AB-001.
Es la contínua lucha entre agencias reguladoras y los cocineros de nuevas drogas.
Lo curioso es qeu en ésta batalla tecnológica, ésta vez las cosas se han desencadenadod e forma rapidísima, eincluso se ha diseñado una app de teléfono iteligente para detectarlo.
Igualmente los autores describen una técnica colorimétrica
Aquí les dejo el trabajo:https://doi.org/10.1016/j.forc.2019.100167
o si prefieren el abstract.
The use of synthetic cannabinoids is an emerging problem
in contemporary society, and the detection techniques currently used do
not meet the requirements of a drug test. We report herein an
inexpensive, in situ method for the detection of the synthetic
cannabinoid AB-001 in herbal samples. The method exploits a colorimetric
kit consisting in a 96 plate well containing a bench stable modified
Ehrlich reagent adsorbed on silica. The colour derived by the
interaction of AB-001 with the detection matrix is read on a RGB (Red,
Green, and Blue) base by using the camera of a smartphone, thus making
the method accessible to everyone.
A calibration curve
of the analyte in the range 1–200 μg was realized, with a MQL (method
quantitation limit) of 1 μg and positive recovery tests from samples of
tobacco and damiana spiked with different amounts of AB-001. The method
presents selectivity for AB-001 with respect to other indole-based
cannabinoids (e.g. JWH-018, JWH-302, whose response is ca 5% of the one
produced by the same concentration of AB-001) and other common drugs
(e.g. acetaminophen, ascorbic acid, bromazepam, fluoxetine), these last
not interfering up to a 100:1 drug:AB-001 ratio.
This
new colorimetric approach would be considered a category C screening
test, and therefore recommended as part of a comprehensive analytical
scheme for the identification of AB-001
